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Animal cell culture is an important biotechnology, which is widely used in vaccine production, monoclonal antibody preparation, recombinant protein expression and tissue engineering. In cell culture, a bioreactor (or bioreactor) is a key piece of equipment that provides the optimal environment for cell growth and metabolism. In recent years, with the development of biomedicine, food and industrial biotechnology, the application prospect of animal cell culture bioreactor is increasingly broad.

Biological fermentation technology is widely used in pharmaceutical, food, environmental protection and bioenergy fields, and the stirring system, as a key component of the fermentation process, has an important impact on the growth of microorganisms, the synthesis of metabolites and fermentation efficiency. Reasonable mixing system design can not only improve the efficiency of dissolved oxygen, promote the mixing of materials, but also maintain a suitable growth environment for microorganisms. This paper will discuss the main role of stirring system in biological fermentation process and its design specification.

In the biological fermentation industry, the cleanliness of the equipment has a crucial impact on the stability of the fermentation process, product quality and production safety. CIP (Clean-in-Place) system is a kind of automatic cleaning system without disassembling equipment, which is widely used in the cleaning and disinfection of fermenters, pipelines, heat exchangers and other equipment. Rational design of CIP cleaning system can not only effectively remove residual pollutants, prevent microbial pollution, but also improve production efficiency, reduce labor costs and cleaning agent consumption. This paper will discuss the application and design specification of CIP cleaning system in biological fermentation industry.

Biological fermentation is a process that relies on microbial metabolic activities to transform substances. It is widely used in food, medicine, environmental protection and bio-chemical industry. pH value is one of the key environmental parameters affecting the fermentation process, which not only directly affects the growth of microorganisms, enzyme activity and the generation of metabolites, but also closely related to the medium composition, oxygen transport and fermenter operation. Therefore, proper pH control is essential to optimize the fermentation process and improve the yield and quality of the target product. This paper will discuss the role of pH in the process of biological fermentation, and analyze the design focus of pH control system.